Perifosine (KRX-0401): Synthetic Alkylphospholipid Akt In...

2026-01-20

Perifosine (KRX-0401) is a synthetic alkylphospholipid Akt inhibitor validated for robust induction of apoptosis in cancer cell models. Its well-characterized mechanism, including caspase activation and PI3K/Akt/mTOR pathway inhibition, positions it as a reliable tool for cancer signaling and neuroprotection research.